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    La dapoxétine est un composé organique de la classe des inhibiteurs sélectifs de la recapture de la sérotonine (ISRS) mais sans effet anti-dépresseur. Il s'agit à ce jour du seul médicament spécifiquement développé pour traiter l'éjaculation précoce, chez les hommes adultes âgés de 18 à 64 ans, et qui bénéficie d'une autorisation de mise sur le marché pour cette indication. Elle permet de multiplier le temps avant éjaculation par trois ou quatre. Contrairement aux autres ISRS utilisés dans cette indication en dehors de toute autorisation, le délai d'action très court (de l'ordre de 60 minutes) permet sa prise à la demande, peu avant le rapport sexuel, plutôt qu'en prise chronique. La durée d'action, elle, varie entre 6 et 8 heures. Il ne doit pas être pris plus d'une fois par 24 heures. La posologie initiale est de 30 milligrammes par jour. viagra pills A szildenafil-citrát egy, a férfi erektilis diszfunkciójának (merevedési zavar) kezelésében alkalmazott gyógyszerhatóanyag. A szert a Pfizer cég fejlesztette ki, és Viagra márkanéven hozta forgalomba. Hatásának kialakulásához szexuális ingerlésre van szükség. A bevétel után a hatás 0,5–2 (átlagosan 1) óra elteltével jelentkezik. A hímvessző erekciójáért a nitrogén-monoxid (NO) vegyület a felelős, amely a pénisz szivacsos állományának sejtjeiben aktiválja a guanilát-cikláz enzimet. Ezen enzim hatására ciklikus guanozin-monofoszfát (c GMP) keletkezik, amely különböző jelátviteli utakon keresztül ellazítja a hímvessző simaizmait, ezzel elősegítve a vér beáramlását és az erekció létrejöttét. A c GMP-t egy foszfodiészteráz enzim (foszfodiészteráz-5(PDE-5))bontja le. A szildenafil ezt a bontóenzimet blokkolja, ezzel tartósan magas c GMP szintet és ezáltal „biztosabb” merevedést hoz létre.

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    Apr 11, 2016. Tadalafil is a prescription medicine used to treat impotence, known medically as erectile dysfunction ED, and symptoms of enlarged prostate. viagra weight loss Cialis, also known as tadalafil or Adcirca, is used to treat erectile dysfunction and pulmonary arterial hypertension. Find out how to use it. Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA on April 27, 2012 and by EMA on June 21, 2013. Avanafil is known by the trademark names.

    Sildenafil (známější pod komerčním názvem Viagra) je prostředek používaný muži na erektilní dysfunkci (impotenci), vyvinutý farmaceutickou společností Pfizer. Jeho účinek spočívá v tom, že inhibuje fosfodiesterázu, jež by jinak rozkládala cyklický GMP. Cyklický GMP následně může stimulovat účinek oxidu dusnatého (NO), látky, která je schopná vyvolat erekci. Sildenafil byl připraven pod kódovým označením UK-92480 skupinou chemiků ve výzkumném ústavu firmy Pfizer v anglickém Sandwichi. Nejprve byl studován jako možný lék na vysoký tlak a anginu pectoris a prošel klinickými testy. Firma Pfizer se tedy následně rozhodla lék nabízet k léčbě erektilní dysfunkce. Lék si patentovala v roce 1996 a v roce 1998 získala povolení amerického úřadu FDA. It was then out-licensed to, and developed by, Vivus Inc. In July 2013 Vivus announced partnership with Menarini Group, which will commercialise and promote Spedra in over 40 European countries plus Australia and New Zealand. Other similar drugs are sildenafil, tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 30–45 minutes.

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  7. La dapoxétine est un composé organique de la classe des inhibiteurs sélectifs de la recapture de la sérotonine ISRS mais sans effet anti-dépresseur.

    • Dapoxétine — Wikipédia
    • Avanafil - Wikipedia
    • Sildenafil - Wikipedia

    Erektil dysfunktion, erektionssvikt, eller, i vardagligt tal och förr 1 impotens, innebär att en man stadigvarande saknar förmåga att få erektion eller att han. clomid cramping after ovulation Sildenafil známější pod komerčním názvem Viagra je prostředek používaný muži na erektilní dysfunkci impotenci, vyvinutý farmaceutickou společností. Tadalafil INN is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction ED under the names Cialis /siˈælɪs/ see-AL-iss, Adcirca /ædˈsɜːrkə/.

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